Chang C S, Lin S F, Lee J C, Chang J G, Liu T C, Huang S M, Chen T P, Liu H W
Division of Hemato-oncology, Kaohsiung Medical College Hospital, Taiwan, Republic of China.
Gaoxiong Yi Xue Ke Xue Za Zhi. 1995 Oct;11(10):574-7.
We described a case of acute promyelocytic leukemia with O blood type who received bone marrow transplantation during a second remission from his HLA identical, B blood type sibling. Using PCR genotyping of the ABO group and analysis of the variable number of tandem repeats of the D1S80 locus, we could quickly document the successful early engraftment in this patient. We emphasize that the use of PCR ABO genotyping is a quick and valuable method which could be applied to assess the engraftment and its follow up in those transplant cases with donors of mismatched blood groups.
我们描述了一例O型血的急性早幼粒细胞白血病患者,他在第二次缓解期接受了来自其HLA配型相同的B型血同胞的骨髓移植。通过对ABO血型进行PCR基因分型以及对D1S80位点串联重复序列可变数目进行分析,我们能够快速证明该患者早期成功植入。我们强调,PCR ABO基因分型的应用是一种快速且有价值的方法,可用于评估血型不匹配供体的移植病例中的植入情况及其随访。