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[口腔鳞状细胞癌的统计分析]

[A statistical analysis of oral squamous cell carcinoma].

作者信息

Chen G S, Chen C H

机构信息

Graduate Institute of Dental Sciences, Kaohsiung Medical College, Taiwan, Republic of China.

出版信息

Gaoxiong Yi Xue Ke Xue Za Zhi. 1995 Oct;11(10):582-8.

PMID:7494240
Abstract

Oral squamous cell carcinoma is the most common malignant tumor of the oral cavity, and it accounts for about 90% of malignant oral tumors. We have retrospectively reviewed 211 patients with oral squamous cell carcinoma which were confirmed by histopathological examination at Kaohsiung Medical College Hospital in the period between 1987 and 1991. There were 194 males and 17 females, with a male to female ratio of 11.4 to 1. The age of the patients ranged from 23 to 95 years, mean 51.96 years, with the greatest incidence of disease in the ages between 40 and 59 years (63.3%). Squamous cell carcinoma occurred most often on the buccal mucosa. There were 40.8% of cases which occurred on the buccal mucosa, 25.6% on the tongue, 17.1% on the gingiva of mandible, 9.5% on the maxilla, 5.2% on the lower lip and 1.9% on the floor of mouth. 195 cases with a recorded history of habits in the patient's medical records were evaluated for the relationships between habits, patient's age and the location of the tumor involved. We have used a general factorial ANOVA to examine the relationship of habits and patients' age. A Hierarchical Loglinear Analysis was used to determine whether there was an association between habits and the location of tumor involved. Of the 195 cases, 144 (73.85%) chewed betel nut regularly. The mean age of the patients with betel nut chewing habits (49.04 years) was significantly younger than that of the patients without betel nut chewing habits (59.27 years) (p = 0.006).(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

口腔鳞状细胞癌是口腔最常见的恶性肿瘤,约占口腔恶性肿瘤的90%。我们回顾性分析了1987年至1991年期间在高雄医学院附属医院经组织病理学检查确诊的211例口腔鳞状细胞癌患者。其中男性194例,女性17例,男女比例为11.4:1。患者年龄在23岁至95岁之间,平均51.96岁,40岁至59岁发病率最高(63.3%)。鳞状细胞癌最常发生于颊黏膜。40.8%的病例发生于颊黏膜,25.6%发生于舌部,17.1%发生于下颌牙龈,9.5%发生于上颌,5.2%发生于下唇,1.9%发生于口底。对病历中有习惯记录的195例患者评估习惯、患者年龄与肿瘤累及部位之间的关系。我们采用一般析因方差分析来检验习惯与患者年龄的关系。采用分层对数线性分析来确定习惯与肿瘤累及部位之间是否存在关联。在195例患者中,144例(73.85%)有经常嚼槟榔的习惯。有嚼槟榔习惯的患者平均年龄(49.04岁)显著低于无嚼槟榔习惯的患者(59.27岁)(p = 0.006)。(摘要截选至250字)

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