Schmidt P, Burck D, Bürger A
Acta Biol Med Ger. 1978;37(8):1305-9.
A single oral administration of 27 mg 11-H-eicosafluorundecanoic acid/kg of body weight (according to 1/20 of the oral LD50; 0.049 mM) resulted in a long lasting hepatomegaly in male rats. This was accompanied by a decrease of the triglyceride and total lipid levels in blood serum, a temporary increase of the total lipids in the liver, and an increase of the hexobarbital sleeping time, the latter being normalized before the liver/body weight ratio reached the control level. The bromothalein elimination and the S-alanine amino transferase and S-alkaline phosphatase activities were not affected.
单次口服27毫克11 - H - 二十氟十一烷酸/千克体重（相当于口服半数致死量的1/20；0.049毫摩尔）会导致雄性大鼠出现持久的肝肿大。同时，血清中的甘油三酯和总脂质水平降低，肝脏中的总脂质暂时增加，己巴比妥睡眠时间延长，在肝/体重比达到对照水平之前，后者已恢复正常。溴酚酞清除率以及S - 丙氨酸氨基转移酶和S - 碱性磷酸酶活性未受影响。
