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Butyrate and colonic cytokinetics: differences between in vitro and in vivo studies.

作者信息

Lupton J R

机构信息

Faculty of Nutrition, Texas A & M University, College Station 77843-2471, USA.

出版信息

Eur J Cancer Prev. 1995 Oct;4(5):373-8. doi: 10.1097/00008469-199510000-00007.

DOI:10.1097/00008469-199510000-00007
PMID:7496326
Abstract
摘要

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Butyrate and colonic cytokinetics: differences between in vitro and in vivo studies.丁酸盐与结肠细胞动力学：体外研究与体内研究的差异
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Effects of short-chain fatty acids on a human colon carcinoma cell line.短链脂肪酸对人结肠癌细胞系的影响。
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Overexpression of heat shock factor 1 inhibits butyrate-induced differentiation in colon cancer cells.
热休克因子1的过表达抑制结肠癌细胞中丁酸盐诱导的分化。
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Increased colonic luminal synthesis of butyric acid is associated with lowered colonic cell proliferation in piglets.仔猪结肠腔内丁酸合成增加与结肠细胞增殖降低有关。
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The gut fermentation product butyrate, a chemopreventive agent, suppresses glutathione S-transferase theta (hGSTT1) and cell growth more in human colon adenoma (LT97) than tumor (HT29) cells.肠道发酵产物丁酸是一种化学预防剂，与肿瘤（HT29）细胞相比，其对人结肠腺瘤（LT97）细胞中谷胱甘肽S-转移酶θ（hGSTT1）和细胞生长的抑制作用更强。
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