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[使用钬:钇铝石榴石(THC:YAG)钬激光进行外路巩膜造口术治疗青光眼]

[External sclerostomy using the THC:YAG Holmium laser in the treatment of glaucoma].

作者信息

Detry-Morel M, Yuksel D

机构信息

Cliniques Universitaires St. Luc (UCL), Bruxelles.

出版信息

Bull Soc Belge Ophtalmol. 1995;255:39-46.

PMID:7496574
Abstract

Ab externo THC:YAG Holmium laser sclerostomy is an interesting alternative to standard full thickness filtering surgery. We report our retrospective experience over a total number of 38 sclerostomies between march 1993 and september 1994 on 32 patients (33 eyes) with primary or secondary glaucomas composed of 17 phakic and 16 aphakic and/or pseudophakic eyes. The mean patient age is 62.9 years (range: 10 to 90 years). The mean follow-up time is 7.5 months (1 to 18 months). We used a long pulsed (300 microsec) laser emitting in the near infrared (2.1 microns). A conjunctival stab incision was made 12 mm away from the sclerostomy site to allow entry of a 22 G probe which delivers energy at a right angle to the long axis of the fiber. We used 100 mJ per pulse laser energy delivered at a rate of 5 impacts per second. The mean delivered energy to produce a functional sclerostomy was 16.1 J. All patients received subconjunctival injections of 5 Fluorouracil (mean number of injections: 7.4). Criteria for success included an IOP of 22 mmH or less with or without additional medical treatment and a decrease of at least 30% of IOP when the preoperative IOP was 22 mmHg or less. The mean preoperative IOP was 35.8 mmHg (21 to 54 mmHg). By 3 months, the mean IOP of the 14 eyes over 19 successfully controlled was 15.2 mmHg (8 to 22 mmHg) with additional medical treatment in 3 cases. By 6 months, 11 eyes over 11 successfully controlled was 14.1 mmHg (6 to 21 mmHg) with additional medical treatment in 3 cases.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

经外路钬

钇铝石榴石激光巩膜造瘘术是标准全层滤过性手术的一种有趣替代方法。我们报告了1993年3月至1994年9月期间对32例患者(33只眼)进行的38次巩膜造瘘术的回顾性经验,这些患者患有原发性或继发性青光眼,其中包括17只晶状体眼和16只无晶状体眼和/或人工晶状体眼。患者平均年龄为62.9岁(范围:10至90岁)。平均随访时间为7.5个月(1至18个月)。我们使用了长脉冲(300微秒)、近红外(2.1微米)发射的激光。在距巩膜造瘘部位12毫米处做一个结膜穿刺切口,以便插入一个22G探头,该探头以与光纤长轴成直角的角度传递能量。我们以每秒5次的冲击速率输送每脉冲100毫焦的激光能量。产生功能性巩膜造瘘术的平均输送能量为16.1焦耳。所有患者均接受了5-氟尿嘧啶的结膜下注射(平均注射次数:7.4次)。成功标准包括眼压为22毫米汞柱或更低(无论是否接受额外药物治疗),以及术前眼压为22毫米汞柱或更低时眼压至少降低30%。术前平均眼压为35.8毫米汞柱(21至54毫米汞柱)。到3个月时,19只眼中14只眼压得到成功控制,平均眼压为15.2毫米汞柱(8至22毫米汞柱),其中3例接受了额外药物治疗。到6个月时,11只眼中11只眼压得到成功控制,平均眼压为14.1毫米汞柱(6至21毫米汞柱),其中3例接受了额外药物治疗。(摘要截断于250字)

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