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短双歧杆菌YIT4064增强派尔集合淋巴结细胞产生抗流感病毒血凝素抗体的能力。

Augmentation of anti-influenza virus hemagglutinin antibody production by Peyer's patch cells with Bifidobacterium breve YIT4064.

作者信息

Yasui H, Nagaoka N, Hayakawa K

机构信息

Yakult Central Institute for Microbiological Research, Tokyo, Japan.

出版信息

Clin Diagn Lab Immunol. 1994 Mar;1(2):244-6. doi: 10.1128/cdli.1.2.244-246.1994.

DOI:10.1128/cdli.1.2.244-246.1994
PMID:7496955
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC368237/
Abstract

Bifidobacterium breve YIT4064 was tested an an adjuvant for oral influenza vaccine by the murine Peyer's patch cell culture method. The organism augmented production of anti-influenza virus hemagglutinin immunoglobulin A antibody by Peyer's patch cells in response to addition of hemagglutinin. These antibodies may be disseminated to the respiratory mucosal tissue and prevent influenza virus infection.

摘要

通过鼠派伊尔结细胞培养方法，对短双歧杆菌YIT4064作为口服流感疫苗佐剂进行了测试。该微生物增强了派伊尔结细胞在添加血凝素后产生的抗流感病毒血凝素免疫球蛋白A抗体。这些抗体可能会扩散到呼吸道黏膜组织并预防流感病毒感染。

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Augmentation of anti-influenza virus hemagglutinin antibody production by Peyer's patch cells with Bifidobacterium breve YIT4064.短双歧杆菌YIT4064增强派尔集合淋巴结细胞产生抗流感病毒血凝素抗体的能力。
Clin Diagn Lab Immunol. 1994 Mar;1(2):244-6. doi: 10.1128/cdli.1.2.244-246.1994.
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本文引用的文献

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Cross-protection in mice infected with influenza A virus by the respiratory route is correlated with local IgA antibody rather than serum antibody or cytotoxic T cell reactivity.经呼吸道感染甲型流感病毒的小鼠中的交叉保护作用与局部IgA抗体相关，而非血清抗体或细胞毒性T细胞反应性。
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The common mucosal immune system and current strategies for induction of immune responses in external secretions.共同黏膜免疫系统及在外分泌液中诱导免疫反应的当前策略。
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Induction, persistence and strain specificity of haemagglutinin-specific secretory antibodies in lungs of mice after intragastric administration of inactivated influenza virus vaccines.经胃内给予灭活流感病毒疫苗后，小鼠肺部血凝素特异性分泌抗体的诱导、持续存在及毒株特异性
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Mechanism of neutralization of influenza virus by secretory IgA is different from that of monomeric IgA or IgG.分泌型 IgA 中和流感病毒的机制不同于单体 IgA 或 IgG 的中和机制。
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Immunogenicity of Bifidobacterium breve and change in antibody production in Peyer's patches after oral administration.短双歧杆菌的免疫原性及口服给药后派尔集合淋巴结中抗体产生的变化
J Dairy Sci. 1989 Jan;72(1):30-5. doi: 10.3168/jds.S0022-0302(89)79076-7.
10
Protection against influenza virus infection by a two-dose regimen of nasal vaccination using vaccines combined with cholera toxin B subunit.使用与霍乱毒素B亚基联合的疫苗进行两剂鼻内接种对流感病毒感染的防护作用。
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