Yasui H, Nagaoka N, Hayakawa K
Yakult Central Institute for Microbiological Research, Tokyo, Japan.
Clin Diagn Lab Immunol. 1994 Mar;1(2):244-6. doi: 10.1128/cdli.1.2.244-246.1994.
Bifidobacterium breve YIT4064 was tested an an adjuvant for oral influenza vaccine by the murine Peyer's patch cell culture method. The organism augmented production of anti-influenza virus hemagglutinin immunoglobulin A antibody by Peyer's patch cells in response to addition of hemagglutinin. These antibodies may be disseminated to the respiratory mucosal tissue and prevent influenza virus infection.
通过鼠派伊尔结细胞培养方法,对短双歧杆菌YIT4064作为口服流感疫苗佐剂进行了测试。该微生物增强了派伊尔结细胞在添加血凝素后产生的抗流感病毒血凝素免疫球蛋白A抗体。这些抗体可能会扩散到呼吸道黏膜组织并预防流感病毒感染。