Caldarera I, Van Herwerden L A, Taams M A, Bos E, Roelandt J R
Department of Cardio-pulmonary Surgery, University Hospital Rotterdam-Dykzigt, Erasmus University, The Netherlands.
Eur Heart J. 1995 Jul;16(7):999-1006. doi: 10.1093/oxfordjournals.eurheartj.a061037.
An essential step in the surgical management of patients with mitral regurgitation, is a thorough understanding of the pathophysiological mechanism. This information can be obtained by multiplane transoesophageal echocardiography which displays all the components of the incompetent valve.
Forty-nine patients were scanned intra-operatively by multiplane transoesophageal echocardiography, and findings compared with those at visual inspection during surgery. The pre-operative diagnosis was prolapse of the anterior mitral leaflet in nine patients (sensitivity 100%, specificity 95%), prolapse of the posterior leaflet in 17 patients (sensitivity 100%, specificity 94%) and prolapse of both leaflets in eight patients (sensitivity 87%, specificity 100%). In 11 patients annular dilatation with no abnormalities in mitral leaflet closure or motion was diagnosed (sensitivity 73%, specificity 100%). Two patients had a false-positive diagnosis of prolapse of the anterior leaflet, two others on the posterior leaflet. A prolapse of both leaflets was overlooked in one patient. Multiplane transoesophageal echocardiography scanned the mitral valve, disclosing the extent of pathology along the closure line of leaflets in 88% of patients with mitral valve prolapse. The antero-posterior diameter of the mitral annulus was measured: a diameter over 35 mm indicated annular dilatation. Using this criterion, sensitivity was 89% and specificity 100%.
Multiplane transoesophageal echocardiography enabled components of the mitral valve to be examined systematically, and provided important information on the pathophysiological mechanism of mitral regurgitation before surgical repair. The method also allowed the surgical outcome to be assessed, offering the possibility of optimal repair.
对于二尖瓣反流患者的手术治疗,关键的一步是深入了解其病理生理机制。多平面经食管超声心动图可获取此信息,它能显示功能不全瓣膜的所有组成部分。
49例患者在手术中接受了多平面经食管超声心动图检查,并将检查结果与手术中直视所见进行比较。术前诊断为前叶脱垂的患者有9例(敏感性100%,特异性95%),后叶脱垂的患者有17例(敏感性100%,特异性94%),双叶脱垂的患者有8例(敏感性87%,特异性100%)。诊断为瓣环扩张但二尖瓣叶关闭或活动无异常的患者有11例(敏感性73%,特异性100%)。有2例前叶脱垂诊断为假阳性,另有2例后叶脱垂诊断为假阳性。有1例患者双叶脱垂被漏诊。多平面经食管超声心动图对二尖瓣进行扫描,在88%的二尖瓣脱垂患者中显示了沿瓣叶闭合线的病变范围。测量了二尖瓣环的前后径:直径超过35 mm表明瓣环扩张。采用此标准,敏感性为89%,特异性为100%。
多平面经食管超声心动图能够系统地检查二尖瓣的各个组成部分,并在手术修复前提供有关二尖瓣反流病理生理机制的重要信息。该方法还可用于评估手术结果,为实现最佳修复提供了可能。