[长爪沙鼠（Meriones unguiculatus）生化基因标记的研究]

[Study of biochemical gene markers in the Mongolian gerbil (Meriones unguiculatus)].

作者信息

Okumura K, Maeda Y, Koresawa Y, Hashiguchi T

机构信息

Toxicology Laboratory, Yoshitomi Pharmaceutical Industries, Ltd., Fukuoka, Japan.

出版信息

Exp Anim. 1995 Oct;43(5):719-23. doi: 10.1538/expanim1978.43.5_719.

DOI:10.1538/expanim1978.43.5_719

PMID:7498338

Abstract

The present study was conducted to analyze biochemical marker genes and to clarify genetic variation in 4 Mongolian gerbil (Meriones unguiculatus) strains (MGS/Sea, MON/Jms Gbs, Kwl: Mongolian Gerbil and Hos: Mongolian gerbil) maintained in Japan. Cellulose acetate, starch gel or agar gel electrophoresis was used. Of the 23 kinds of proteins detected, variation was found only in liver acid phosphatase (Acp2); no variation in other proteins was found within or among strains. The results suggest that these 4 Mongolian gerbil strains are genetically similar. A strain difference was found in the Acp2 locus of liver acid phosphatase. The Kwl: Mongolian Gerbil strain had a band of Acp2 locus, whereas MGS/Sea, MON/Jms and Hos: Mongolian gerbil strains did not.

摘要

本研究旨在分析生化标记基因，并阐明在日本饲养的4个蒙古沙鼠（Meriones unguiculatus）品系（MGS/Sea、MON/Jms Gbs、Kwl：蒙古沙鼠和Hos：蒙古沙鼠）的遗传变异。采用醋酸纤维素、淀粉凝胶或琼脂凝胶电泳。在检测到的23种蛋白质中，仅在肝脏酸性磷酸酶（Acp2）中发现变异；在品系内或品系间的其他蛋白质中未发现变异。结果表明这4个蒙古沙鼠品系在遗传上相似。在肝脏酸性磷酸酶的Acp2位点发现了品系差异。Kwl：蒙古沙鼠品系有Acp2位点的条带，而MGS/Sea、MON/Jms和Hos：蒙古沙鼠品系没有。