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[与酒精性慢性钙化性胰腺炎相关的AW23和AW24(作者译)]

[AW23 and AW24 associated with chronic calcifying pancreatitis of alcoholic origin (author's transl)].

作者信息

Dani R, Antunes L J, Rocha W M, Nogueira C E

出版信息

Arq Gastroenterol. 1978 Oct-Dec;15(4):163-6.

PMID:749853
Abstract

Determinations of histocompatibility antigens of A and B loci was undertaken in 22 white male patients with chronic calcifying pancreatitis (CCP) of alcoholic etiology and compared to 100 controls. Results were analysed by the kappa2 test with Yates correction. HLA--AW23 and AW24 were significantly more prevalent in patients than in controls and HLA-B8 was absent in all CCP cases. Although the small number of cases is insufficient to allow any definite conclusion, the obtained data suggests the presence of a genetic predisposition to this disease.

摘要

对22名病因是酒精性的慢性钙化性胰腺炎(CCP)白人男性患者进行了A和B位点组织相容性抗原的测定,并与100名对照者进行了比较。结果采用Yates校正的kappa2检验进行分析。HLA - AW23和AW24在患者中的流行率显著高于对照者,且在所有CCP病例中均未发现HLA - B8。虽然病例数量较少,不足以得出任何明确结论,但所获得的数据表明存在对该疾病的遗传易感性。

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1
[AW23 and AW24 associated with chronic calcifying pancreatitis of alcoholic origin (author's transl)].[与酒精性慢性钙化性胰腺炎相关的AW23和AW24(作者译)]
Arq Gastroenterol. 1978 Oct-Dec;15(4):163-6.
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Dig Dis Sci. 1981 May;26(5):449-52. doi: 10.1007/BF01313589.
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Evidence for an inherited predisposition to alcoholic pancreatitis. A controlled HLA typing study.酒精性胰腺炎遗传易感性的证据。一项对照HLA分型研究。
Dig Dis Sci. 1984 Aug;29(8):727-30. doi: 10.1007/BF01312945.
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