Cavallo R
Istituto di Microbiologia dell'Università di Torino.
G Batteriol Virol Immunol. 1992;85(1-12):35-46.
NK Lymphocytes were first identified by their cytotoxic and cytolytic activity against tumor cells. However there is now increasing evidence that these cells are also mediators of natural resistance against viruses, fungi, protozoa and bacteria. The purpose of this review is to summarize the data on the antimicrobial activity of NK cells and to discuss the influence of corticoids and of other molecules interfering with innate resistance against pathogenic micro-organisms.
自然杀伤(NK)淋巴细胞最初是因其对肿瘤细胞的细胞毒性和溶细胞活性而被识别出来的。然而,现在越来越多的证据表明,这些细胞也是对病毒、真菌、原生动物和细菌产生天然抵抗力的介质。这篇综述的目的是总结关于NK细胞抗菌活性的数据,并讨论皮质类固醇和其他干扰对病原微生物天然抵抗力的分子的影响。