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梗死腮腺的病理组织学表现(坏死性涎腺化生)(作者译)

[Pathohistological findings in infarcted parotid glands (necrotizing sialometaplasia) (author's transl)].

作者信息

Donath K

出版信息

Arch Otorhinolaryngol. 1978 Nov 22;219(2):392-3. doi: 10.1007/BF00463844.

Abstract

In 1973 Abrams et al. described a nonneoplastic lesion named "necrotizing sialometaplasia". Since this date additional cases have been reported. The lesion might be misdiagnosed either mucoid tumor or squamous carcinoma. The cases reported in the following years were localised on the hard palate, lower lip, nose and in the major salivary glands. By the "Speicheldrüsenregister" of the Institute of Pathology of the University of Hamburg five cases of infarcted parotid glands were registered during the years of 1965--1977. All infarcts are observed in patients with tumors in the parotid region. No infarct happened spontaneously. Histologically two forms of infarcts are distinguished: haemorrhagic and ischaemic. In both forms of infarcts there necrosis of acini and squamous metaplasia in intercalar and striated ducts. Degenerative changes are seen in the center of ducts with squamous metaplasia. The reaction of the interstices of the two forms of infarction are different: In the ischaemic there lipomatosis, and in the haemorrhagic there are fibrosis. Our findings are exactly as described for minor salivary glands in necrotizing sialometaplasia.

摘要

1973年,艾布拉姆斯等人描述了一种名为“坏死性涎腺化生”的非肿瘤性病变。自那时起,又有更多病例被报道。该病变可能被误诊为黏液瘤或鳞状细胞癌。在接下来的几年里报道的病例位于硬腭、下唇、鼻子以及大唾液腺。通过汉堡大学病理学研究所的“涎腺登记册”,在1965年至1977年期间登记了5例腮腺梗死病例。所有梗死病例均见于腮腺区域有肿瘤的患者。没有自发发生梗死的情况。组织学上,梗死可分为两种类型:出血性和缺血性。在这两种类型的梗死中,腺泡均有坏死,闰管和纹状管有鳞状化生。在有鳞状化生的导管中心可见退行性改变。两种类型梗死的间质反应不同:缺血性梗死有脂肪化生,出血性梗死有纤维化。我们的发现与坏死性涎腺化生中小唾液腺的描述完全一致。

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