拟南芥的辐射敏感突变体。
Radiation-sensitive mutants of Arabidopsis thaliana.
作者信息
Jenkins M E, Harlow G R, Liu Z, Shotwell M A, Ma J, Mount D W
机构信息
Department of Molecular and Cellular Biology, University of Arizona, Tucson 85721, USA.
出版信息
Genetics. 1995 Jun;140(2):725-32. doi: 10.1093/genetics/140.2.725.
Abstract
Five Arabidopsis mutants have been isolated on the basis of hypersensitivity of leaf tissue to UV light. For each mutant, the UV-hypersensitive phenotype (uvh) was inherited as a single recessive Mendelian trait. In addition, each uvh mutant represented a separate complementation group. Three of the mutations producing the UV hypersensitive phenotype have been mapped relative to either genetic markers or physical microsatellite polymorphisms. Locus UVH1 is linked to nga76 on chromosome 5, UVH3 to GL1 on chromosome three, and UVH6 to nga59 on chromosome 1. Each uvh mutant has a characteristic pattern of sensitivity based on UV sensitivity of leaf tissue, UV sensitivity of root tissue, and ionizing radiation sensitivity of seeds. On the basis of these patterns, possible molecular defects in these mutants are discussed.
摘要
已根据叶片组织对紫外线的超敏反应分离出五个拟南芥突变体。对于每个突变体，紫外线超敏表型（uvh）作为单一隐性孟德尔性状遗传。此外，每个uvh突变体代表一个单独的互补群。产生紫外线超敏表型的三个突变已相对于遗传标记或物理微卫星多态性进行了定位。UVH1基因座与5号染色体上的nga76连锁，UVH3与3号染色体上的GL1连锁，UVH6与1号染色体上的nga59连锁。每个uvh突变体都有基于叶片组织的紫外线敏感性、根组织的紫外线敏感性和种子的电离辐射敏感性的特征性敏感模式。基于这些模式，讨论了这些突变体中可能的分子缺陷。
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