Matsuo K, Kuniyasu C, Yamada S, Susumi S, Yamamoto S
Avian Dis. 1978 Oct-Dec;22(4):552-61.
The suppressive effect of Mycoplasma gallisepticum (MG) on Haemophilus gallinarum (HG) immune response was shown. Antibody response to HG was highly suppressed when chickens were inoculated intramuscularly with HG-MG combined bacterin. Findings were similar in chickens injected intramuscularly with HG and MG bacterin separately at adjacent sites. No immunosuppressive effect was recognized when injections with HG and MG bacterins were in the left and right thigh muscles, respectively, or from intravenous inoculation with the combined bacterin. Nor did HG-Mycoplasma synoviae (MS) combined bacterin injected intramuscularly evidence immunosuppression. Recovery rate of HG and clinical symptoms were more evident in chickens with suppression of antibody responses than in chickens without suppression.
结果表明，鸡毒支原体（MG）对鸡嗜血杆菌（HG）的免疫反应具有抑制作用。当鸡肌肉注射HG-MG联合菌苗时，对HG的抗体反应受到高度抑制。在相邻部位分别肌肉注射HG菌苗和MG菌苗的鸡中也观察到了类似的结果。当分别在左右大腿肌肉注射HG和MG菌苗，或静脉注射联合菌苗时，未发现免疫抑制作用。肌肉注射HG-滑液支原体（MS）联合菌苗也未显示出免疫抑制作用。与未受抑制的鸡相比，抗体反应受到抑制的鸡中HG的恢复率和临床症状更为明显。
