Carrette M, Brock P, Uyttebroeck A, Van Geet C, Segers K, Casteels-Van Daele M
Afd. Kindergeneeskunde, Universitaire Ziekenhuizen, Leuven.
Ned Tijdschr Geneeskd. 1995 Nov 18;139(46):2375-7.
In four patients, all girls, aged 2, 3.5, 4 and 5 years, transient erythroblastopenia was diagnosed. The children were presented because of acute pallor. The haemoglobin levels were 2.8 to 5.0 mmol/l. After 3 weeks all patients had recovered or were recovering with increasing haemoglobin values. Three of the four patients needed one blood transfusion. In two patients there was evidence of a parvovirus B19 infection. Transient erythroblastopenia is mostly seen in patients aged 1-4 years. Most cases are postinfectious and there is evidence that human parvovirus B19 is responsible for many cases. In the very young child the differential diagnosis from Blackfan-Diamond anaemia may be very difficult.
在4例均为女童、年龄分别为2岁、3.5岁、4岁和5岁的患者中,诊断为暂时性红细胞生成减少症。这些患儿因急性面色苍白前来就诊。血红蛋白水平为2.8至5.0毫摩尔/升。3周后,所有患者均已康复或正在康复,血红蛋白值不断上升。4例患者中有3例需要输血1次。2例患者有B19细小病毒感染的证据。暂时性红细胞生成减少症多见于1至4岁的患者。大多数病例为感染后发病,有证据表明许多病例是由人B19细小病毒引起的。对于幼儿,与先天性纯红细胞再生障碍性贫血进行鉴别诊断可能非常困难。