De Caluwé J P, Gilbert L, Alexander M
Hôpital d'Etterbeek-Ixelles, Bruxelles.
Rev Med Brux. 1993 May;14(5):141-4.
Severe pure red cell anaemia due to B19 parvovirus infection is reported in a child with haemoglobin SC disease. B19 parvovirus infection was demonstrated by specific IgM. Although hypoplastic crisis occurring in SC children is usually less frequent and more benign than in sickle- cell anaemia, it necessitated several blood transfusions in our patient. The child recovered rapidly and was discharged after 12 days. This case again illustrates the role of HPV-B19 in the development of transient red cell aplasia occurring in patients with haemolytic anaemia. However, it is unusual since in the few reported children with HbSC disease and HPV-B19 infection, aregenerative anaemia remained moderate and did not generally require blood transfusions.
据报道，一名患有血红蛋白SC病的儿童因B19细小病毒感染而出现严重纯红细胞贫血。通过特异性IgM证实了B19细小病毒感染。虽然SC儿童发生的再生障碍危象通常比镰状细胞贫血患者更少见且病情更轻，但我们的患者仍需要多次输血。患儿恢复迅速，12天后出院。该病例再次说明了HPV-B19在溶血性贫血患者发生短暂红细胞再生障碍中的作用。然而，这一病例并不常见，因为在少数报道的患有HbSC病和HPV-B19感染的儿童中，再生障碍性贫血仍然较轻，一般不需要输血。
