Sires U I, Mallory S B
Division of Dermatology, Washington University School of Medicine, St Louis, MO 63110, USA.
Postgrad Med. 1995 Dec;98(6):79-84, 86.
Dampness, maceration, fecal enzymes, chemicals, and other irritants lead to diaper dermatitis in infants. Most cases can be cleared with frequent diaper changes, use of superabsorbent disposable diapers (which contain gelling material in their core), and a low-potency topical corticosteroid. If the eruption lasts for more than 3 days or classic erythematous satellite lesions are present, addition of an antifungal agent should help resolve the condition. Recalcitrant or clinically atypical eruptions may signify rarer disorders, such as psoriasis, Langerhans' cell histiocytosis, Leiner's disease, or acrodermatitis enteropathica. Patients with these conditions should be referred to a dermatologist, if possible, for further evaluation and treatment.
潮湿、浸渍、粪便酶、化学物质及其他刺激物会导致婴儿尿布皮炎。大多数病例通过频繁更换尿布、使用高吸水性一次性尿布(其核心含有胶凝材料)以及低效外用皮质类固醇即可治愈。如果皮疹持续超过3天或出现典型的红斑卫星状损害,则加用抗真菌药有助于缓解病情。顽固性或临床非典型皮疹可能意味着更罕见的疾病,如银屑病、朗格汉斯细胞组织细胞增多症、莱纳病或肠病性肢端皮炎。如有可能,患有这些疾病的患者应转诊至皮肤科医生处进行进一步评估和治疗。