Leyden J J, Kligman A M
Arch Dermatol. 1978 Jan;114(1):56-9.
A quantitative microbiological survey of multiple sites in the diaper area in 40 normal infants and 100 infants with various forms of diaper dermatitis showed (1) no significant differences between normal infants and those with common chafing form of diaper dermatitis except for a low number of Staphylococcus aureus organisms in 50% of those with chafing dermatitis compared to no S aureus in normals; (2) S aureus occurred in high numbers in every case of atopic dermatitis and was frequently found at much lower levels in psoriasis, seborrheic dermatitis, and chafing dermatitis; (3) Candida albicans occurred in 80% of cases clinically diagnosed as moniliasis localized to the diaper area and in 33% of those suspected of Candida infection with dissemination beyond the diaper area, while C albicans was found in only five of 145 culture sites in 40 normal infants.
对40名正常婴儿和100名患有各种形式尿布皮炎的婴儿的尿布区域多个部位进行的定量微生物学调查显示：（1）正常婴儿与患有常见擦烂型尿布皮炎的婴儿之间无显著差异，只是50%擦烂性皮炎婴儿中存在少量金黄色葡萄球菌，而正常婴儿中未发现金黄色葡萄球菌；（2）在每例特应性皮炎病例中金黄色葡萄球菌数量都很多，在银屑病、脂溢性皮炎和擦烂性皮炎病例中也经常能发现数量少得多的金黄色葡萄球菌；（3）白色念珠菌在临床诊断为局限于尿布区域的念珠菌病的80%病例中出现，在怀疑念珠菌感染且感染扩散至尿布区域以外的病例中占33%，而在40名正常婴儿的145个培养部位中仅在5个部位发现白色念珠菌。
