Labbate L A, Fava M, Oleshansky M, Zoltec J, Littman A, Harig P
Department of Psychiatry, Walter Reed Army Medical Center, Washington, DC 20307, USA.
Psychosomatics. 1995 Nov-Dec;36(6):555-60. doi: 10.1016/s0033-3182(95)71611-5.
This study evaluated the relationship between two biochemical risk factors for coronary artery disease, serum lipids and dehydroepiandrosterone-sulfate (DHEA-S), and both fitness and perceived stress among a cohort of senior male Army officers (N = 331). The participants underwent a number of assessments gauging their fitness [exercise tolerance as measured by maximum ventilatory oxygen uptake (MVO2)], psychological well-being, and biochemical cardiovascular risk factors. Perceived stress was significantly and inversely related to DHEA-S levels, even after adjusting for age, though no relationship was found between perceived stress and serum lipids. Significant correlations were found between MVO2 and high-density lipoprotein cholesterol and inversely between MVO2 and triglycerides. Overall, the study's findings are generally consistent with the view that psychological stress and physical activity have opposite effects on parameters that affect cardiovascular status.
本研究评估了一组高级陆军男性军官（N = 331）中两种冠心病生化风险因素——血脂和硫酸脱氢表雄酮（DHEA-S）与健康状况及感知压力之间的关系。参与者接受了多项评估，以测量他们的健康状况[通过最大通气摄氧量（MVO2）衡量运动耐量]、心理健康状况以及心血管生化风险因素。即使在调整年龄后，感知压力仍与DHEA-S水平显著负相关，不过未发现感知压力与血脂之间存在关联。发现MVO2与高密度脂蛋白胆固醇之间存在显著相关性，而MVO2与甘油三酯之间呈负相关。总体而言，该研究结果与心理压力和身体活动对影响心血管状况的参数具有相反作用这一观点基本一致。
