Nedellec V, Fontaine A, Luciolli E, Bourdillon F
Médicins Sans Frontières, Paris.
Rev Epidemiol Sante Publique. 1995;43(5):485-93.
Old peeling paint with high content of lead has been identified as the main source of lead poisoning for children screened in Paris since 1985. In 1989, Médecins Sans Frontières and Migration Santé tested abatement methods in 59 homes of severely lead-poisoned children. The effectiveness of abatement is evaluated with respect to the evolution in dust lead contents and of the children's blood lead levels. Lead content wsas measured in dust samples collected from the floor of the homes before abatement, then every three months after abatement; results are available for 24 homes. Blood lead levels were assessed in the course of the children's medical follow-up; results are available before and after abatement for 78 children living in 41 of the abated homes. The effect of abatement on the children's blood lead level was assessed through multivariate analysis. The median decrease in dust lead contents was 365 micrograms/m2 one to two months after abatement and 300 micrograms/m2 three to six months after abatement. However, dust lead contents of more than 1,000 micrograms/m2 were found in more than half of the communal areas of the buildings six to twenty-eight months after abatement. For 2 of the families, abatement was associated with an increase in the children's blood lead-levels. For all of the other children, abatement was associated with a significant decrease in blood lead levels, controlling for the child's age and initial lead poisoning level, and for the overall downward trend in blood lead levels over time since the initial screening.(ABSTRACT TRUNCATED AT 250 WORDS)
自1985年以来,含铅量高的旧剥落油漆已被确定为巴黎筛查出的儿童铅中毒的主要来源。1989年,无国界医生组织和移民健康组织在59户重度铅中毒儿童家庭中测试了清除方法。清除效果根据灰尘铅含量和儿童血铅水平的变化进行评估。在清除前从房屋地板采集灰尘样本测量铅含量,然后在清除后每三个月测量一次;24户家庭有结果。在儿童医疗随访过程中评估血铅水平;41户已清除房屋中有78名儿童在清除前后有结果。通过多变量分析评估清除对儿童血铅水平的影响。清除后一到两个月,灰尘铅含量的中位数下降为365微克/平方米,三到六个月后为300微克/平方米。然而,在清除后六到二十八个月,超过一半的建筑物公共区域灰尘铅含量超过1000微克/平方米。有2个家庭的清除与儿童血铅水平升高有关。对于所有其他儿童,在控制儿童年龄和初始铅中毒水平以及自初次筛查以来血铅水平随时间的总体下降趋势后,清除与血铅水平显著下降有关。(摘要截于250字)