Bonnyns M, Bourdoux P
Département de Médecine, Hôpital Universitaire Saint-Pierre.
Rev Med Brux. 1995 Nov;16(5):361-3.
Two types of thyroid biochemical abnormalities (TBA) are observed in AIDS. The unspecific TBA are similar to TBA reported in the Euthyroid Sick Syndrome. An increased serum TBG of unknown origin and a decreased circulating rT3 are the most specific TBA of AIDS. The latter abnormality may be in relation with an elevated level of TNF. The frequency of serum antithyroid antibodies seems higher than in control groups. Opportunistic infections of the thyroid gland or destruction of the thyroid by Kaposi's sarcoma are also reported in AIDS.
在艾滋病患者中观察到两种类型的甲状腺生化异常(TBA)。非特异性TBA与甲状腺功能正常的病态综合征中报道的TBA相似。血清甲状腺素结合球蛋白(TBG)来源不明地增加以及循环中反三碘甲状腺原氨酸(rT3)降低是艾滋病最具特异性的TBA。后一种异常可能与肿瘤坏死因子(TNF)水平升高有关。血清抗甲状腺抗体的频率似乎高于对照组。艾滋病患者中也有甲状腺的机会性感染或卡波西肉瘤对甲状腺的破坏的报道。