Sharp A A, O'Neil M B, Abbott L F, Marder E
Dept of Biology, Brandeis University, Waltham, MA 02254.
Trends Neurosci. 1993 Oct;16(10):389-94. doi: 10.1016/0166-2236(93)90004-6.
The dynamic clamp is a novel method that uses computer simulation to introduce conductances into biological neurons. This method can be used to study the role of various conductances in shaping the activity of single neurons, or neurons within networks. The dynamic clamp can also be used to form circuits from previously unconnected neurons. This approach makes computer simulation an interactive experimental tool, and will be useful in many applications where the role of synaptic strengths and intrinsic properties in neuronal and network dynamics is of interest.
动态钳是一种利用计算机模拟向生物神经元引入电导的新方法。该方法可用于研究各种电导在塑造单个神经元或网络中神经元活动方面的作用。动态钳还可用于由先前未连接的神经元形成电路。这种方法使计算机模拟成为一种交互式实验工具，在许多关注突触强度和内在特性在神经元及网络动力学中作用的应用中都将很有用。
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