Collet E, Dalac S, Maerens B, Courtois J M, Izac M, Lambert D
Department of Dermatology, Hôpital du Bocage, Dijon, France.
Br J Dermatol. 1994 Feb;130(2):231-4. doi: 10.1111/j.1365-2133.1994.tb02906.x.
High-dose intravenous gammaglobulin (IVGG) has proved to be effective in the treatment of a number of immune disorders. We report two patients with juvenile dermatomyositis (DM) who improved with IVGG therapy. These patients had become refractory to corticosteroids and had developed unacceptable steroid toxicity. We suggest that IVGG can be useful in the treatment of juvenile DM, by reducing steroid requirements, and replacing immunosuppressive drugs.
大剂量静脉注射丙种球蛋白（IVGG）已被证明在治疗多种免疫性疾病中有效。我们报告了两名青少年皮肌炎（DM）患者，他们接受IVGG治疗后病情有所改善。这些患者对皮质类固醇治疗无效，并出现了难以接受的类固醇毒性。我们认为IVGG可用于治疗青少年皮肌炎，通过减少对类固醇的需求，并替代免疫抑制药物。
