Billing L, Eriksson M, Jonsson B, Steneroth G, Zetterström R
Department of Pediatrics, Karolinska Institute, St. Göran's Children's Hospital, Stockholm, Sweden.
Child Abuse Negl. 1994 Jan;18(1):3-9. doi: 10.1016/0145-2134(94)90091-4.
Sixty-five children born to women who all used amphetamine during pregnancy were followed prospectively up to the age of 8 years. There was a statistically significant correlation between the extent (among and duration) of amphetamine exposure during fetal life and psychometric tests, aggressive behavior, adjustment and general assessment, indicating a worse outcome for children who had been more exposed to the drug. Alcohol use during pregnancy as well as attitude towards pregnancy also showed a statistical correlation to the outcome. Predictors of the child's psychosocial environment were few and only maternal psychiatric treatment, alcohol abuse and number of custodians correlated with aggressive behavior and general assessment.
对65名母亲在孕期均使用过苯丙胺的儿童进行了前瞻性追踪,直至他们8岁。胎儿期苯丙胺暴露的程度(范围和持续时间)与心理测试、攻击性行为、适应能力及综合评估之间存在统计学上的显著相关性,这表明接触该药物较多的儿童预后较差。孕期饮酒以及对怀孕的态度也与结果存在统计学相关性。儿童心理社会环境的预测因素较少,只有母亲接受精神科治疗、酗酒和监护人数量与攻击性行为及综合评估相关。