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[Evaluation of globular osmotic resistance (GOR) and of the lysis test with glycerol (GLT/50) in the screening of heterozygous thalassemia].

作者信息

Deledda R, Russino G, Inzaina A

出版信息

Quad Sclavo Diagn. 1978 Jun;14(2):259-65.

PMID:751101
Abstract

A rapid and simple procedure measuring the rate of hemolysis of 50% of erytrocytes suspended in a standardized glycerol mixture (GLT/50) has been compared with the erytrocyte osmotic fragility to NaCl 0.375% concentration, carried out according to Parpat's method modified, in order to estimate the respective behaviour in the screening of beta-thalassemia trait. The GLT/50 is provided with more selectivity especially between beta-thalassemia trait carriers and other subjects with iron deficiency anemia.

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