急性期反应
The acute phase response.
作者信息
Baumann H, Gauldie J
机构信息
Dept of Molecular and Cell Biology, Roswell Park Cancer Institute, Buffalo, NY 14263.
出版信息
Immunol Today. 1994 Feb;15(2):74-80. doi: 10.1016/0167-5699(94)90137-6.
PMID:7512342
Abstract
Adult mammals respond to tissue damage by implementing the acute phase response, which comprises a series of specific physiological reactions. This review outlines the principal cellular and molecular mechanisms that control initiation of the tissue response at the site of injury, the recruitment of the systemic defense mechanisms, the acute phase response of the liver and the resolution of the acute phase response.
摘要
成年哺乳动物通过启动急性期反应来应对组织损伤，急性期反应包括一系列特定的生理反应。本综述概述了控制损伤部位组织反应起始、全身防御机制募集、肝脏急性期反应以及急性期反应消退的主要细胞和分子机制。
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