Demura H, Jibiki K, Demura R
Dept. of Medicine, Institute of Clinical Endocrinology, Tokyo Women's Medical College.
Nihon Rinsho. 1994 Mar;52(3):642-7.
The problem and recent progress of radioimmunoassay for various kinds of synthetic steroid hormones are reviewed. The specificity and sensitivity depend mostly on the position of synthetic antigen (hemisuccinate or oxime). Using good antibodies, a direct radioimmunoassay without extraction procedures of samples is available. A simplified method is required for the monitoring of synthetic steroids to know the effects and side effects.
综述了各类合成甾体激素放射免疫分析的问题及近期进展。特异性和灵敏度主要取决于合成抗原(半琥珀酸盐或肟)的位置。使用优质抗体,无需对样品进行提取程序即可进行直接放射免疫分析。为了解合成甾体激素的作用和副作用,需要一种简化方法来监测它们。