一位家庭主妇因大米引发的哮喘和接触性荨麻疹。

Asthma and contact urticaria caused by rice in a housewife.

作者信息

Lezaun A, Igea J M, Quirce S, Cuevas M, Parra F, Alonso M D, Martín J A, Cano M S

机构信息

Servicio de Alergología, Hospital Ramón y Cajal, Madrid, Spain.

出版信息

Allergy. 1994 Feb;49(2):92-5. doi: 10.1111/j.1398-9995.1994.tb00806.x.

DOI:10.1111/j.1398-9995.1994.tb00806.x

PMID:7513507

Abstract

We report the case of an atopic housewife who presented with rhinoconjunctivitis-asthma and contact urticaria from handling rice and other cereals. She tolerated cooke cereals. Both skin prick tests with a rice extract (20% w/v) and a rub test with raw rice gave positive results. Bronchial challenge test with methacholine revealed a PC20 of 0.45 mg/ml. The challenge test with raw rice resulted in immediate and late clinical and spirometric responses; pretreatment with DSCG inhibited both responses. The histamine release test (HRT) with rice was positive, and we detected rice-specific IgE antibodies by REIA in the patient's serum. Skin prick tests, HRT, and RAST with a battery of cereals gave positive results. Finally, the rice REIA was inhibited by rice (75%), rye (63%), corn (64%), and wheat (51%) extracts.

摘要

我们报告了一例特应性家庭主妇的病例，她因接触大米和其他谷物而出现 rhinoconjunctivitis - 哮喘和接触性荨麻疹。她能耐受煮熟的谷物。用大米提取物（20% w/v）进行的皮肤点刺试验和用生大米进行的摩擦试验均呈阳性。用乙酰甲胆碱进行的支气管激发试验显示 PC20 为 0.45 mg/ml。用生大米进行的激发试验导致即刻和迟发性临床及肺功能反应；用色甘酸钠预处理可抑制这两种反应。大米的组胺释放试验（HRT）呈阳性，我们通过放射免疫分析（REIA）在患者血清中检测到大米特异性 IgE 抗体。用一系列谷物进行的皮肤点刺试验、HRT 和放射性变应原吸附试验（RAST）均呈阳性。最后，大米 REIA 被大米（75%）、黑麦（63%）、玉米（64%）和小麦（51%）提取物抑制。