Swertifrancheside, an HIV-reverse transcriptase inhibitor and the first flavone-xanthone dimer, from Swertia franchetiana.
作者信息
Wang J N, Hou C Y, Liu Y L, Lin L Z, Gil R R, Cordell G A
机构信息
Department of Phytochemistry, Institute of Medicinal Plant Development, Beijing, People's Republic of China.
出版信息
J Nat Prod. 1994 Feb;57(2):211-7. doi: 10.1021/np50104a003.
PMID:7513747
Abstract
The first flavone-xanthone C-glucoside, swertifrancheside, was isolated from Swertia franchetiana, and its structure was elucidated on the basis of spectroscopic analysis as 1,5,8-trihydroxy-3-methoxy-7-(5',7',3'',4''- tetrahydroxy-6'-C-beta-D-glucopyranosyl-4'-oxy-8'-flavyl)-xanthone . This compound was a moderately potent inhibitor of HIV reverse transcriptase.
摘要
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