Lemperière T
Acta Psychiatr Belg. 1978 Sep-Oct;78(5):715-23.
Our concept of depression have been profondly modified during these last decennies. The work of Kraepelin keeps an interest more than historical. By proposing a medical model for thymic troubles, he has opened the avenue for genetic and biochemical research which will confirm or not the nosology based on clinical investigations. Other models have been proposed for affective troubles : psychodynamic, ethological and experimental models. It is not yet possible to make a synthesis integrating psychological and biological parameters.
在过去几十年里，我们对抑郁症的概念有了深刻的改变。克雷佩林的著作如今所具有的意义已不仅仅是历史性的。他提出了一种针对精神障碍的医学模型，为基因和生化研究开辟了道路，而这些研究将会证实或否定基于临床调查的疾病分类学。针对情感障碍还提出了其他模型：心理动力学模型、行为学模型和实验模型。目前还无法将心理和生物学参数进行综合。
