Pedal W P, Warzok R W, Hufnagl P, Roth K
Department of Neuropathology, University of Greifswald, Deutschland.
Zentralbl Pathol. 1994 Mar;140(1):89-94.
79 astrocytic tumors classified according to the WHO classification and stained with a modified AgNOR staining technique were analysed with the help of an automatic image analysing system. The number and area of AgNORs were determined. The mean AgNOR number per nucleus was 1.28 in pilocytic, 1.98 in differentiated, 2.84 in anaplastic astrocytomas, 3.33 in small cell glioblastomas and 4.24 in multiforme glioblastomas. The area of all AgNORs per cell ranged from 0.95 microns2 (pilocytic astrocytomas), 1.53 microns2 (differentiated astrocytomas), 2.73 microns2 (anaplastic astrocytomas), 3.1 microns2 (small cell glioblastomas) to 4.12 microns2 (multiforme glioblastomas). With regard to AgNORs there are little differences between anaplastic astrocytomas and small cell glioblastomas.
利用自动图像分析系统，对79例根据世界卫生组织（WHO）分类法分类并用改良银染核仁组织区（AgNOR）染色技术染色的星形细胞瘤进行了分析。测定了AgNORs的数量和面积。每核AgNORs的平均数量在毛细胞型星形细胞瘤中为1.28，在分化型中为1.98，在间变性星形细胞瘤中为2.84，在小细胞胶质母细胞瘤中为3.33，在多形性胶质母细胞瘤中为4.24。每个细胞所有AgNORs的面积范围从0.95平方微米（毛细胞型星形细胞瘤）、1.53平方微米（分化型星形细胞瘤）、2.73平方微米（间变性星形细胞瘤）、3.1平方微米（小细胞胶质母细胞瘤）到4.12平方微米（多形性胶质母细胞瘤）。关于AgNORs，间变性星形细胞瘤和小细胞胶质母细胞瘤之间几乎没有差异。
