Ugawa Y, Hanajima R, Kanazawa I
Department of Neurology, School of Medicine, University of Tokyo, Japan.
Electroencephalogr Clin Neurophysiol. 1994 Jun;93(3):225-9. doi: 10.1016/0168-5597(94)90044-2.
We studied the effects of a subthreshold magnetic stimulus over the motor cortex and an electrical stimulus over the cerebellum on EMG responses produced by a suprathreshold magnetic stimulus over the motor cortex. In normal subjects, both subthreshold conditioning stimuli and cerebellar stimuli could suppress responses to suprathreshold magnetic test stimuli when given at appropriate timings: "cortico-cortical" and "cerebellar" inhibition, respectively. In all patients with degenerative ataxias and patients with a lesion in the cerebellar thalamus, the "cortico-cortical" inhibition was normal and the "cerebellar" inhibition was absent. We conclude that cerebellar systems make no or little contribution to the above-mentioned "cortico-cortical" inhibition.
我们研究了运动皮层阈下磁刺激以及小脑电刺激对运动皮层阈上磁刺激所产生的肌电图反应的影响。在正常受试者中，当在适当时间给予时，阈下条件刺激和小脑刺激都能分别抑制对阈上磁测试刺激的反应，即分别为“皮质-皮质”抑制和“小脑”抑制。在所有患有退行性共济失调的患者以及小脑丘脑有病变的患者中，“皮质-皮质”抑制正常，而“小脑”抑制缺失。我们得出结论，小脑系统对上述“皮质-皮质”抑制没有或几乎没有贡献。
