Synthesis of 4-alkoxyaryl beta-D-glucopyranosides and their inhibitory effects on histamine release from rat peritoneal mast cells induced by concanavalin A.
作者信息
Wang T C, Furukawa H, Nihro Y, Kakegawa H, Matsumoto H, Satoh T
机构信息
Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Japan.
出版信息
Chem Pharm Bull (Tokyo). 1994 Mar;42(3):570-5. doi: 10.1248/cpb.42.570.
PMID:7516266
Abstract
The inhibitory effects of newly synthesized 4-alkoxyaryl beta-D-glucopyranosides on histamine release from rat peritoneal mast cells induced by concanavalin A were examined. A plot of hydrophobicity (k') against inhibitory activity of the compounds showed a distinct maximum, and 4-decyloxy-2,3,6-trimethylphenyl beta-D-glucopyranoside was the most potent inhibitor among the tested compounds.
摘要
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