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产生κ型本-周蛋白的口咽髓外浆细胞瘤。

Extramedullary plasmacytoma of the oropharynx producing kappa-type Bence-Jonas protein.

作者信息

Fujitani T, Ogasawara H, Hattori H, Isobe T

出版信息

Auris Nasus Larynx. 1978;5(2):71-5. doi: 10.1016/s0385-8146(78)80009-1.

Abstract

A case of extramedullary plasmacytoma in the oropharynx of a 41 year-old woman is reported. Histologically, the tumor was plasmacytoma consisting mainly of matured plasma cells and showing a deposit of amyloid in the interstitial structure. Immunoelectrophoretic studies of the concentrated urine specimen revealed a kappa-type Bence-Jones protein even though there was no increase in blood M-protein. Lineac electron radiation of 5,100 rad was given over a period of eight weeks but no effect was noted. After the tumor was surgically removed, follow up of the patient was made for 2 years without evidence of recurrence or metastasis.

摘要

报告了一例41岁女性口咽髓外浆细胞瘤病例。组织学上,肿瘤为浆细胞瘤,主要由成熟浆细胞组成,间质结构中有淀粉样物质沉积。浓缩尿标本的免疫电泳研究显示存在κ型本-周蛋白,尽管血液M蛋白没有增加。在八周内给予5100拉德的直线加速器电子辐射,但未观察到效果。肿瘤手术切除后,对患者进行了2年随访,无复发或转移迹象。

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