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金黄色葡萄球菌中与噬菌体相关的肠毒素A、葡萄球菌激酶和β毒素的转化

Phage-related conversion of enterotoxin A, staphylokinase and beta-toxin in Staphylococcus aureus.

作者信息

Zabicka D, Młynarczyk A, Windyga B, Młynarczyk G

机构信息

Department of Clinical Bacteriology, Medical Academy of Warsaw.

出版信息

Acta Microbiol Pol. 1993;42(3-4):235-41.

PMID:7516614
Abstract

The conversion of enterotoxin A, staphylokinase and beta-toxin in Staphylococcus aureus is related with lysogeny stage. Bacteriophages able to convert enterotoxin A were used for lysogenization of the standard NCTC 8325-4 strain. Lysogenic, enterotoxigenic derivatives of this strain were characterized. The conversion of enterotoxin A was obtained in 7 examined derivatives, the conversion of enterotoxin A and staphylokinase at the same time was obtained in one case and the loss of beta hemolysin production ability was observed in all of 8 examined derivatives of the NCTC 8325-4 standard strain.

摘要

金黄色葡萄球菌中肠毒素A、葡萄球菌激酶和β毒素的转化与溶原化阶段有关。能够转化肠毒素A的噬菌体被用于标准NCTC 8325 - 4菌株的溶原化。对该菌株的溶原性、产肠毒素衍生物进行了表征。在7个检测的衍生物中获得了肠毒素A的转化,在1个案例中同时获得了肠毒素A和葡萄球菌激酶的转化,并且在NCTC 8325 - 4标准菌株的所有8个检测衍生物中均观察到β溶血素产生能力的丧失。

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