Vecchioli Scaldazza C
Divisione di Urologia, Ospedale Civile di Jesi.
Minerva Urol Nefrol. 1993 Dec;45(4):151-4.
62 men with prostatic hypertrophy and bladder obstruction and 31 age matched women without lower urinary tract obstruction, underwent urodynamic testing which included uroflowmetry, gas cystometry, urethral pressure measurement: electromyography and pressure flow study was only performed to the patients with prostatic hypertrophy. No patient with neurological disease, diabetes mellitus, pelvic operation, neoplasm or stone of the bladder was admitted to the study. Involuntary detrusor contractions (unstable detrusor) were found in 74.2% of male patients and in 25.8% of female patients. In male patients aged over 72 the percentage was 81.8% while in the female patients of the same age was 60%. All the 62 male patients underwent prostatectomy. Two months after surgery, acystometry was done. Unstable detrusor was found in 63.1% of cases. Patients over 80 had a percentage of 100%. These data suggest obstructive prostatic hypertrophy as an important factor in development of involuntary bladder contractions, but the primary pathophysiological factor appears to be age of patients.
62例患有前列腺增生和膀胱梗阻的男性以及31例年龄匹配但无下尿路梗阻的女性接受了尿动力学检查,检查项目包括尿流率测定、气体膀胱测压、尿道压力测量:仅对前列腺增生患者进行了压力流率研究。研究未纳入患有神经系统疾病、糖尿病、盆腔手术史、肿瘤或膀胱结石的患者。74.2%的男性患者和25.8%的女性患者发现有逼尿肌不自主收缩(不稳定逼尿肌)。72岁以上男性患者的这一比例为81.8%,而同龄女性患者为60%。所有62例男性患者均接受了前列腺切除术。术后两个月进行了膀胱测压。63.1%的病例发现有不稳定逼尿肌。80岁以上患者的比例为100%。这些数据表明梗阻性前列腺增生是膀胱不自主收缩发生的一个重要因素,但主要的病理生理因素似乎是患者的年龄。