Removal of t-butyldimethylsilyl protection in RNA-synthesis. Triethylamine trihydrofluoride (TEA, 3HF) is a more reliable alternative to tetrabutylammonium fluoride (TBAF).
作者信息
Westman E, Strömberg R
机构信息
Department of Organic Chemistry, Arrhenius Laboratory, Stockholm University, Sweden.
出版信息
Nucleic Acids Res. 1994 Jun 25;22(12):2430-1. doi: 10.1093/nar/22.12.2430.
Abstract
摘要
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本文引用的文献
1
Effect of excess water on the desilylation of oligoribonucleotides using tetrabutylammonium fluoride.过量水对使用四丁基氟化铵进行寡核糖核苷酸脱硅反应的影响。
Nucleic Acids Res. 1993 Oct 11;21(20):4739-41. doi: 10.1093/nar/21.20.4739.
2
Evaluation of 2'-hydroxyl protection in RNA-synthesis using the H-phosphonate approach.使用H-膦酸酯法评估RNA合成中2'-羟基的保护作用。
Nucleic Acids Res. 1994 Jan 11;22(1):94-9. doi: 10.1093/nar/22.1.94.
3
Studies on the t-butyldimethylsilyl group as 2'-O-protection in oligoribonucleotide synthesis via the H-phosphonate approach.通过H-膦酸酯法进行寡核糖核苷酸合成中叔丁基二甲基硅烷基作为2'-O-保护基的研究。
Nucleic Acids Res. 1988 Oct 11;16(19):9285-98. doi: 10.1093/nar/16.19.9285.
4
Chemical synthesis of a biologically active natural tRNA with its minor bases.具有稀有碱基的生物活性天然转运RNA的化学合成。
Nucleic Acids Res. 1992 Oct 11;20(19):5159-66. doi: 10.1093/nar/20.19.5159.
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