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A new method for removal of the 2'-TBDMS group under acidic conditions in chemical synthesis of RNA.

作者信息

Kawahara S, Wada T, Sekine M

机构信息

Department of Life Science, Faculty of Bioscience and Biotechnology, Tokyo Institute of Technology, Yokohama, Japan.

出版信息

Nucleic Acids Symp Ser. 1995(34):29-30.

PMID:8841536
Abstract

A new and convenient method for removal of the TBDMS group as a protecting group for the 2' hydroxyl function in chemical synthesis of RNA under mild acidic conditions by use of diluted acetic acid solutions and 0.01 M hydrochloric acid (pH 2.0) was developed.

摘要

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