Durkin M S, Davidson L L, Desai P, Hasan Z M, Khan N, Shrout P E, Thorburn M J, Wang W, Zaman S S
Gertrude H. Sergievsky Center, Faculty of Medicine, Columbia University, New York, NY 10032.
Epidemiology. 1994 May;5(3):283-9.
An international study to validate the Ten Questions screen for serious childhood disability was undertaken in communities in Bangladesh, Jamaica, and Pakistan, where community workers screened more than 22,000 children ages 2-9 years. All children who screened positive, as well as random samples of those who screened negative, were referred for clinical evaluations. Applying comparable diagnostic criteria, the sensitivity of the screen for serious cognitive, motor, and seizure disabilities is acceptable (80-100%) in all three populations, whereas the positive predictive values range from 3 to 15%. These results confirm the usefulness of the Ten Questions as a low-cost and rapid screen for these disabilities, although not for vision and hearing disabilities, in populations where few affected children have previously been identified and treated. They also show that the value of the Ten Questions for identifying disability in underserved populations is limited to that of a screen; more thorough evaluations of children screened positive are necessary to distinguish true- from false-positive results and to identify the nature of the disability if present.
一项验证针对儿童严重残疾的十问筛查法的国际研究在孟加拉国、牙买加和巴基斯坦的社区开展，社区工作者对超过22000名2至9岁儿童进行了筛查。所有筛查呈阳性的儿童以及部分筛查呈阴性的随机样本儿童均被转诊进行临床评估。应用可比的诊断标准，在这三个人口中，该筛查法对严重认知、运动和癫痫残疾的敏感度均可接受（80%-100%），而阳性预测值范围为3%至15%。这些结果证实了十问筛查法作为一种低成本且快速的针对这些残疾的筛查方法的有用性，不过在先前很少发现和治疗受影响儿童人口中，它不适用于视力和听力残疾筛查。研究还表明，十问筛查法在服务不足人口中识别残疾的价值仅限于筛查；对筛查呈阳性的儿童进行更全面的评估对于区分真阳性和假阳性结果以及确定残疾性质（如果存在）是必要的。
