Göhmann S, Manning P A, Alpert C A, Walker M J, Timmis K N
Department of Microbiology, GBF-National Research Centre for Biotechnology, Braunschweig, Germany.
Microb Pathog. 1994 Jan;16(1):53-64. doi: 10.1006/mpat.1994.1005.
The O-antigen polysaccharide of the lipopolysaccharide of Shigella dysenteriae serotype 1 is encoded by determinants located on a 9 kb plasmid (rfp) and on the chromosome near the his locus (rfb). Molecular genetic and biochemical studies of the rfp determinant reported here show that the rfp region contains two genes, rfpA and rfpB, lying in an operon. rfpB was demonstrated to encode a membrane-bound galactosyl-transferase. The low G+C content of rfp DNA suggests that it did not originate in Shigella.
痢疾志贺氏菌1型脂多糖的O抗原多糖由位于9 kb质粒（rfp）以及his位点（rfb）附近染色体上的决定簇编码。本文报道的rfp决定簇的分子遗传学和生物化学研究表明，rfp区域包含位于一个操纵子中的两个基因rfpA和rfpB。已证明rfpB编码一种膜结合半乳糖基转移酶。rfp DNA的低G+C含量表明它并非起源于志贺氏菌。
