Nwankwo M U, Okuonghae H O, Currier G, Schuit K E
Department of Child Health, University of Benin, Nigeria.
Ann Trop Paediatr. 1994;14(2):125-30. doi: 10.1080/02724936.1994.11747704.
The prevalence of respiratory syncytial virus (RSV) infection among severely malnourished children was studied at the University of Benin Teaching Hospital, Benin City, Nigeria at a time when the infection was known to be prevalent in the community. Nasopharyngeal washings were obtained from subjects on admission and thereafter every 4 days until discharge. RSV was detected by ELISA technique. Of 20 well nourished children who served as controls, 11 were ELISA-positive for RSV (55%). Eight (16%) of the 51 patients who were malnourished were ELISA-positive, four of whom (8%) had nosocomial infection. Fever and rhinitis were the most common presenting features in the RSV-infected malnourished children. None of the children showed any clinical or radiological signs of lower respiratory tract infection. Malnourished children appear not to be at increased risk of RSV infection, and those who contract the infection usually do not manifest severe disease.
在尼日利亚贝宁城贝宁大学教学医院，当已知社区中呼吸道合胞病毒（RSV）感染流行时，对重度营养不良儿童中的RSV感染患病率进行了研究。在受试者入院时采集鼻咽冲洗液，此后每4天采集一次，直至出院。采用酶联免疫吸附测定（ELISA）技术检测RSV。在作为对照的20名营养良好的儿童中，11名ELISA检测RSV呈阳性（55%）。51名营养不良患者中有8名（16%）ELISA检测呈阳性，其中4名（8%）发生了医院感染。发热和鼻炎是RSV感染的营养不良儿童最常见的表现特征。没有儿童出现任何下呼吸道感染的临床或放射学征象。营养不良儿童似乎没有增加RSV感染的风险，感染该病毒的儿童通常不会表现出严重疾病。
