Louboutin J P, Maugard-Louboutin C, Fumoleau P
Unité CNRS 1340, Hôpital G.R.-Laennec, Nantes, France.
Eur Neurol. 1994;34(4):236-8. doi: 10.1159/000117046.
Esthesioneuroblastoma is a rare neoplasm of neuroectodermal origin, arising from the olfactory epithelium in the roof of the nasal cavity. Extension to the brain can occur less frequently than local recurrence, but leptomeningeal metastases without brain involvement have rarely been mentioned. We report 2 cases with poor prognosis of leptomeningeal infiltration during the evolution of esthesioneuroblastoma.
嗅神经母细胞瘤是一种起源于神经外胚层的罕见肿瘤，由鼻腔顶部的嗅上皮发生。其向脑部的扩展不如局部复发常见，但很少提及无脑实质受累的软脑膜转移。我们报告2例嗅神经母细胞瘤病程中发生软脑膜浸润且预后不良的病例。
