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[激光前列腺切除术作为良性前列腺增生症经尿道前列腺切除术的替代方法]

[Laser prostatectomy as alternative to transurethral prostate resection in benign prostatic hyperplasia].

作者信息

Boon T A, van Swol C F, van Venrooij G E, de Gier R P, Verdaasdonk R M

机构信息

Afd. Urologie, Academisch Ziekenhuis, Utrecht.

出版信息

Ned Tijdschr Geneeskd. 1994 Aug 27;138(35):1760-3.

PMID:7523960
Abstract

OBJECTIVE

Assessment of the results of laser prostatectomy, as a treatment for benign prostatic hyperplasia (BPH).

DESIGN

Prospective case control study.

SETTING

University Hospital Utrecht, the Netherlands.

METHOD

Between February 1992 and May 1993, 54 men with their micturition complaints due to BPH were treated with laser prostatectomy (TULIP system). Results were assessed using the international prostatic symptom score (IPSS), the maximal flow and urodynamic tests. The results were compared retrospectively with results of transurethral resection of the prostate (TURP; n = 40): both groups were urodynamically identical.

RESULTS

Of the 54 patients, 10 could not be evaluated 6 months after treatment (5 of them underwent TURP or a second laser prostatectomy). In 40 patients complete evaluation including urodynamics before and six months after treatment was possible. A significant decrease in the symptom score from 19.3 (SD: 7.6) to 6.3 (SD: 5.4) and increase of the maximal flow during pressure-flow studies from 9.6 to 15.8 ml per second were observed. The decrease of the voiding pressure at 6 months after TURP in comparison with laser prostatectomy was close to significance (p = 0.05); the other improvements after urodynamics were comparable.

CONCLUSION

Laser prostatectomy is a promising new therapy for BPH.

摘要

目的

评估激光前列腺切除术治疗良性前列腺增生(BPH)的效果。

设计

前瞻性病例对照研究。

地点

荷兰乌得勒支大学医院。

方法

1992年2月至1993年5月,54例因BPH出现排尿问题的男性接受了激光前列腺切除术(TULIP系统)。使用国际前列腺症状评分(IPSS)、最大尿流率和尿动力学检查评估结果。将结果与经尿道前列腺切除术(TURP;n = 40)的结果进行回顾性比较:两组尿动力学情况相同。

结果

54例患者中,10例在治疗6个月后无法评估(其中5例接受了TURP或二次激光前列腺切除术)。40例患者能够进行包括治疗前和治疗6个月后的尿动力学检查在内的完整评估。观察到症状评分从19.3(标准差:7.6)显著降至6.3(标准差:5.4),压力-流率研究中的最大尿流率从每秒9.6毫升增加到15.8毫升。与激光前列腺切除术相比,TURP术后6个月排尿压力的降低接近显著水平(p = 0.05);尿动力学检查后的其他改善情况相当。

结论

激光前列腺切除术是一种有前景的BPH新疗法。

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