Takeshita M, Kubo O, Hiyama H, Tajika Y, Izawa M, Kagawa M, Takakura K, Kobayashi N, Toyoda M
Department of Neurosurgery, Tokyo Women's Medical College.
Neurol Med Chir (Tokyo). 1994 Jul;34(7):436-9. doi: 10.2176/nmc.34.436.
The intracapsular cholesterol, protein, and calcium contents of epidermoid and dermoid cysts from seven patients were compared with the signal intensities on T1-weighted spin-echo magnetic resonance (MR) images. All specimens had a paste-like consistency when resected. Epidermoid and dermoid cysts demonstrated a wide range of cholesterol and calcium contents, and epidermoid cysts were not always rich in cholesterol. Five patients had cysts with lower signal intensity than white matter, which contained more than 18.3 mg/g wet weight of protein. One of these patients had the highest cholesterol content of all seven patients (22.25 mg/g wet weight) and another had the highest calcium content (0.75 mg/g wet weight). Two patients had cysts with higher signal intensity than white matter, with protein contents of lower than 4.3 mg/g wet weight. High protein content (> 18.3 mg/g wet weight) may decrease signal intensity on T1-weighted MR images, while low protein content (< 4.3 mg/g wet weight) may increase signal intensity in epidermoid and dermoid cysts with high viscosity (paste-like consistency) contents.
将7例患者表皮样囊肿和皮样囊肿的囊内胆固醇、蛋白质和钙含量与T1加权自旋回波磁共振（MR）图像上的信号强度进行了比较。所有标本切除时均呈糊状。表皮样囊肿和皮样囊肿的胆固醇和钙含量范围广泛，且表皮样囊肿并不总是富含胆固醇。5例患者的囊肿信号强度低于白质，其蛋白质含量超过18.3 mg/g湿重。其中1例患者的胆固醇含量在所有7例患者中最高（22.25 mg/g湿重），另1例患者的钙含量最高（0.75 mg/g湿重）。2例患者的囊肿信号强度高于白质，蛋白质含量低于4.3 mg/g湿重。高蛋白含量（>18.3 mg/g湿重）可能会降低T1加权MR图像上的信号强度，而低蛋白含量（<4.3 mg/g湿重）可能会增加具有高粘度（糊状）内容物的表皮样囊肿和皮样囊肿的信号强度。
