Lu-Yao G L, Barry M J, Chang C H, Wasson J H, Wennberg J E
Center for the Evaluative Clinical Sciences, Dartmouth Medical School, Hanover, New Hampshire.
Urology. 1994 Nov;44(5):692-8; discussion 698-9. doi: 10.1016/s0090-4295(94)80208-4.
The purpose of this study was to examine the epidemiology of transurethral resection of the prostate (TURP) and associated risks among Medicare beneficiaries during the period of 1984 to 1990.
Medicare hospital claims for a 20% national sample of Medicare beneficiaries were used to identify TURPs performed during the study period. All reported rates were adjusted to the composition of the 1990 Medicare population. Risks of mortality and reoperation were evaluated using life-table methods.
The age-adjusted rate of TURP reached a peak in 1987 and declined thereafter. Similar trends were observed for all age groups. In 1990, the rates of TURP (including all indications) were approximately 25, 19, and 13 per 1000 for men over the age of 75, 70 to 74, and 65 to 69, respectively. The 30-day mortality following TURP for the treatment of benign prostatic hyperplasia (BPH) decreased from 1.20% in 1984 to 0.77% in 1990 (linear trend, p = 0.0001). The cumulative incidence of a second TURP among men with BPH has likewise decreased steadily over time; in this study, the average was 7.2% over 7 years (5.5% when the indication for the second TURP was restricted to BPH only).
The rate of TURP has been declining since 1987, conceivably due to increasing availability of alternative treatments or changes in treatment preferences of patients and physicians. Over the same period, the outcomes following TURPs have improved, perhaps due to improved surgical care and changes in patient selection.
本研究旨在调查1984年至1990年期间医疗保险受益人中经尿道前列腺切除术(TURP)的流行病学情况及相关风险。
利用医疗保险医院对20%全国医疗保险受益人样本的索赔数据来确定研究期间进行的TURP手术。所有报告的发病率都根据1990年医疗保险人群的构成进行了调整。使用生命表方法评估死亡率和再次手术的风险。
TURP的年龄调整发病率在1987年达到峰值,此后下降。所有年龄组均观察到类似趋势。1990年,75岁以上、70至74岁和65至69岁男性的TURP发病率(包括所有适应症)分别约为每1000人25例、19例和13例。治疗良性前列腺增生(BPH)的TURP术后30天死亡率从1984年的1.20%降至1990年的0.77%(线性趋势,p = 0.0001)。BPH男性患者再次进行TURP的累积发病率也随时间稳步下降;在本研究中,7年的平均发病率为7.2%(当第二次TURP的适应症仅限于BPH时为5.5%)。
自1987年以来,TURP的发病率一直在下降,这可能是由于替代治疗方法的可用性增加或患者和医生治疗偏好的变化。在同一时期,TURP术后的结果有所改善,这可能是由于手术护理的改善和患者选择的变化。