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[情绪性疼痛应激对大鼠脑中神经肽加工酶羧肽酶N活性的影响]

[The effect of emotional-pain stress on the activity of carboxypeptidase N--the enzyme of neuropeptide processing in the rat brain].

作者信息

Gengin M T, Vernigora A N

出版信息

Fiziol Zh Im I M Sechenova. 1994 Mar;80(3):23-7.

PMID:7527703
Abstract

Activity of carboxypeptidase N [correction of H] increased under emotional-algic stress in the rat pituitary gland and hypothalamus. Carboxypeptidase N [correction of H] seems to be involved in development of the stress response, and soluble forms of the enzyme take part in processing of secretory peptides. Membrane-bound forms take part in processing of the neuropeptides specific by their central action.

摘要

在情绪性疼痛应激状态下,大鼠垂体和下丘脑内的羧肽酶N(H校正)活性增加。羧肽酶N(H校正)似乎参与应激反应的发生,该酶的可溶性形式参与分泌肽的加工过程。膜结合形式参与对具有中枢作用特异性的神经肽的加工。

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