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Proteinaceous bacterial toxins and pathogenesis of sepsis syndrome and septic shock: the unknown connection.

作者信息

Bhakdi S, Grimminger F, Suttorp N, Walmrath D, Seeger W

机构信息

Institute of Medical Microbiology, University of Mainz, Germany.

出版信息

Med Microbiol Immunol. 1994 Jul;183(3):119-44. doi: 10.1007/BF00196048.

DOI:10.1007/BF00196048
PMID:7527897
Abstract
摘要

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Proteinaceous bacterial toxins and pathogenesis of sepsis syndrome and septic shock: the unknown connection.蛋白质类细菌毒素与脓毒症综合征及感染性休克的发病机制：未知的联系
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本文引用的文献

1
In vivo effects of intravascularly applied Escherichia coli hemolysin: dissociation between induction of granulocytopenia and lethality in monkeys.血管内注射大肠杆菌溶血素的体内效应：猕猴中性粒细胞减少症的诱导与致死率之间的分离。
Med Microbiol Immunol. 1993 Mar;182(1):1-12. doi: 10.1007/BF00195946.
2
Pore-forming bacterial toxins potently induce release of nitric oxide in porcine endothelial cells.成孔细菌毒素可有效诱导猪内皮细胞释放一氧化氮。
J Exp Med. 1993 Jul 1;178(1):337-41. doi: 10.1084/jem.178.1.337.
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Staphylococcal alpha-toxin induced ventilation-perfusion mismatch in isolated blood-free perfused rabbit lungs.
Virulence. 2010 Jul-Aug;1(4):223-35. doi: 10.4161/viru.1.4.11466.
4
Characterization of recombinant terrelysin, a hemolysin of Aspergillus terreus.重组土曲霉溶血素的特性研究。
Mycopathologia. 2011 Jan;171(1):23-34. doi: 10.1007/s11046-010-9343-0. Epub 2010 Jul 15.
5
Nanopore Detector based analysis of single-molecule conformational kinetics and binding interactions.基于纳米孔探测器的单分子构象动力学和结合相互作用分析。
BMC Bioinformatics. 2006 Sep 6;7 Suppl 2(Suppl 2):S21. doi: 10.1186/1471-2105-7-S2-S21.
6
Formation of ring-shaped structures on erythrocyte membranes after treatment with botulinolysin, a thiol-activated hemolysin from Clostridium botulinum.用肉毒杆菌溶血素（一种来自肉毒梭菌的硫醇激活溶血素）处理后，红细胞膜上形成环形结构。
Infect Immun. 1998 Jun;66(6):2987-90. doi: 10.1128/IAI.66.6.2987-2990.1998.
7
Toxin production by Campylobacter spp.弯曲杆菌属细菌产生毒素
Clin Microbiol Rev. 1997 Jul;10(3):466-76. doi: 10.1128/CMR.10.3.466.
8
Selective killing of human monocytes and cytokine release provoked by sphingomyelinase (beta-toxin) of Staphylococcus aureus.金黄色葡萄球菌鞘磷脂酶（β-毒素）引发的人单核细胞选择性杀伤及细胞因子释放
Infect Immun. 1996 Aug;64(8):2974-9. doi: 10.1128/iai.64.8.2974-2979.1996.
9
Pore-forming toxins trigger shedding of receptors for interleukin 6 and lipopolysaccharide.成孔毒素可引发白细胞介素6和脂多糖受体的脱落。
Proc Natl Acad Sci U S A. 1996 Jul 23;93(15):7882-7. doi: 10.1073/pnas.93.15.7882.
10
Novel pathogenic mechanism of microbial metalloproteinases: liberation of membrane-anchored molecules in biologically active form exemplified by studies with the human interleukin-6 receptor.微生物金属蛋白酶的新型致病机制：以人白细胞介素-6受体研究为例，生物活性形式的膜锚定分子的释放
Infect Immun. 1996 Sep;64(9):3646-51. doi: 10.1128/iai.64.9.3646-3651.1996.
葡萄球菌α毒素在离体无血灌注兔肺中诱导通气-灌注不匹配。
J Appl Physiol (1985). 1993 Apr;74(4):1972-80. doi: 10.1152/jappl.1993.74.4.1972.
4
Endotoxin primes perfused rabbit lungs for enhanced vasoconstrictor response to staphylococcal alpha-toxin.内毒素使灌注的兔肺致敏，增强其对葡萄球菌α毒素的血管收缩反应。
Am Rev Respir Dis. 1993 Nov;148(5):1179-86. doi: 10.1164/ajrccm/148.5.1179.
5
A guide to the use of pore-forming toxins for controlled permeabilization of cell membranes.用于细胞膜可控通透化的成孔毒素使用指南。
Med Microbiol Immunol. 1993 Sep;182(4):167-75. doi: 10.1007/BF00219946.
6
Staphylococcal alpha-toxin kills human keratinocytes by permeabilizing the plasma membrane for monovalent ions.葡萄球菌α毒素通过使质膜对单价离子通透来杀死人类角质形成细胞。
Infect Immun. 1993 Dec;61(12):4972-9. doi: 10.1128/iai.61.12.4972-4979.1993.
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Histidine residues near the N terminus of staphylococcal alpha-toxin as reporters of regions that are critical for oligomerization and pore formation.葡萄球菌α-毒素N端附近的组氨酸残基作为对寡聚化和孔形成至关重要区域的报告分子。
Infect Immun. 1994 Jun;62(6):2249-56. doi: 10.1128/iai.62.6.2249-2256.1994.
8
Novel path to apoptosis: small transmembrane pores created by staphylococcal alpha-toxin in T lymphocytes evoke internucleosomal DNA degradation.凋亡的新途径：葡萄球菌α毒素在T淋巴细胞中形成的小跨膜孔引发核小体间DNA降解。
Infect Immun. 1994 Apr;62(4):1304-12. doi: 10.1128/iai.62.4.1304-1312.1994.
9
Severe VA/Q mismatch in perfused lungs evoked by sequential challenge with endotoxin and E. coli hemolysin.内毒素和大肠杆菌溶血素序贯激发诱导灌注肺中出现严重的通气/血流比值失调。
J Appl Physiol (1985). 1994 Mar;76(3):1020-30. doi: 10.1152/jappl.1994.76.3.1020.
10
Streptococcal toxins (streptolysin O, streptolysin S, erythrogenic toxin).链球菌毒素（链球菌溶血素O、链球菌溶血素S、致热外毒素）。
Pharmacol Ther. 1980;11(3):661-717. doi: 10.1016/0163-7258(80)90045-5.