Pană C, Naftali Z, Gyöngyösi M, Szöts G, Nagy F, Popa N, Braic M, Crăciun C, Nistor V, Eşianu M, Boţianu A, Gross R, Ghidro A
Rev Chir Oncol Radiol O R L Oftalmol Stomatol Chir. 1978 Nov-Dec;27(6):421-6.
The study includes 390 patients of different age, operated for various conditions during the last quarter of 1975, and systematically treated post operatively with heparin (the cases in which heparin was contraindicated were not included). None of the patients developed signs of thromboembolism after the operation. The drawbacks of the method are virtually inexistent as compared to the gravity of postoperative thrombolic complications. A further study included 1708 operated patients of whom 223 (13.0%) received the heparin treatment and 1485 (87.0%) did not. There was no thrombolic-embolic complication in the former lot and 12 cases (0.8%) in the latter. Three of 15 patients (20%) in whom the postoperative heparin treatment was interrupted immediately or very soon, developed thromboembolism. The method is efficient provided it is applied after the operation up to complete mobilization of the patient. The method is readily applicable, there is no risk and haemostasis is insured.
该研究纳入了390例不同年龄的患者，这些患者于1975年最后一个季度因各种病症接受了手术，并在术后系统性地接受了肝素治疗（肝素禁忌的病例未纳入）。术后没有患者出现血栓栓塞迹象。与术后血栓形成并发症的严重性相比，该方法的缺点几乎不存在。另一项研究纳入了1708例接受手术的患者，其中223例（13.0%）接受了肝素治疗，1485例（87.0%）未接受。前一组没有血栓栓塞并发症，后一组有12例（0.8%）。术后立即或很快中断肝素治疗的15例患者中有3例（20%）发生了血栓栓塞。该方法在术后应用直至患者完全活动自如时是有效的。该方法易于应用，没有风险且能确保止血。
