Rivanera D, Lorino G, Lilli D, Dicuonzo G, Mancini C
Istituto di Microbiologia, Facoltà di Medicina e Chirurgia La Sapienza, Rome, Italy.
Eur J Epidemiol. 1994 Apr;10(2):235-7. doi: 10.1007/BF01730378.
The development of new immunodiagnostic systems to study antibodies anti-HCV based on the use of synthetic peptides are potentially very important in the evaluation of indeterminate samples. We have compared two immunodiagnostic tests, the 3-RIBA and LIA-HCV test system, to examine the samples rated as indeterminate by the 2-RIBA test. The results showed that the specificity of the new tests has improved, in fact 29/40 of the indeterminate samples studied became positive with both tests. However, the 3-RIBA test showed higher sensitivity, since two samples negative by LIA-HCV, were positive with this system.
基于合成肽使用来研究抗丙型肝炎病毒抗体的新型免疫诊断系统的开发，在不确定样本的评估中可能非常重要。我们比较了两种免疫诊断测试，即3-RIBA和LIA-HCV测试系统，以检查被2-RIBA测试评定为不确定的样本。结果表明，新测试的特异性有所提高，实际上所研究的40个不确定样本中有29个在两种测试中均呈阳性。然而，3-RIBA测试显示出更高的灵敏度，因为有两个LIA-HCV测试呈阴性的样本在该系统中呈阳性。
