Kimura M, Mizumoto T, Namikawa S, Yada I
Department of Thoracic and Cardiovascular Surgery, Mie University School of Medicine, Tsu.
Jpn J Clin Oncol. 1994 Dec;24(6):316-21.
The prognoses of T4 lung cancer patients treated surgically were investigated in 76 patients. Extended resection was performed in 21 patients, palliative resection in 21 and exploratory thoracotomy in 34. Although the five-year survival of the extended resection group did not differ significantly from that obtained in the exploratory thoracotomy group, the mean survival time of the extended resection group was 3.1 months longer than that of the exploratory thoracotomy group. Two patients who had undergone resection for left atrial involvement, survived for two years or more, and a T4N0 patient with squamous cell carcinoma, in whom resection for aortic involvement was carried out, died from an unrelated disease after 15 months. Two patients with pleural dissemination, who underwent panpleuropneumonectomy, survived for two years. Surgical intervention did not improve the prognosis of patients with N2-squamous cell carcinoma, those with malignant effusion or those with multiple organ involvement.
对76例接受手术治疗的T4期肺癌患者的预后进行了调查。21例行扩大切除术，21例行姑息性切除术，34例行剖胸探查术。尽管扩大切除组的五年生存率与剖胸探查组相比无显著差异，但扩大切除组的平均生存时间比剖胸探查组长3.1个月。2例因左心房受累而接受切除术的患者存活了两年或更长时间，1例T4N0期鳞状细胞癌患者因主动脉受累接受了切除术，15个月后死于无关疾病。2例胸膜播散患者接受了全胸膜肺切除术，存活了两年。手术干预并未改善N2期鳞状细胞癌患者、有恶性胸腔积液患者或有多器官受累患者的预后。
