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电化学疗法(ECT)治疗恶性肿瘤的进展

Advances in the treatment of malignant tumours by electrochemical therapy (ECT).

作者信息

Xin Y L

机构信息

Department of Biomedical Engineering, Hauzhong University of Science and Technology, China.

出版信息

Eur J Surg Suppl. 1994(574):31-5.

PMID:7531017
Abstract

A total of 4,081 patients with various malignant tumours were treated by electrochemical therapy (ECT) at 66 hospitals in China during the period 1987-1992. The clinical effectiveness of ECT was analysed in 2,516 patients who had complete hospital records. The most common malignant tumours treated with ECT was lung cancer (n = 593), skin cancer (n = 401), liver cancer (n = 388) and breast cancer (n = 228). Two thousand one hundred and twenty-four patients were followed up for 1 to 5 years. Survival rates were 84.3% for 1 year, 79.1% for 2 years, 63.5% for 3 years, 57.8% for 4 years, and 46.6% for 5 years. The 5-year survival for T1 and T2 stages was significantly better than for T3 and T4 stages (66.7% vs. 27.1%, p < 0.05). The short-term objective response (complete and partial response) was 78.1%. ECT is indicated in patients who are unsuitable for operation and radio- or chemotherapy due to old age, and who suffer from general weakness, or insufficiency of vital organs.

摘要

1987年至1992年期间,中国66家医院共对4081例患有各种恶性肿瘤的患者进行了电化学疗法(ECT)治疗。对2516例有完整住院记录的患者的ECT临床疗效进行了分析。接受ECT治疗的最常见恶性肿瘤是肺癌(n = 593)、皮肤癌(n = 401)、肝癌(n = 388)和乳腺癌(n = 228)。2124例患者接受了1至5年的随访。1年生存率为84.3%,2年生存率为79.1%,3年生存率为63.5%,4年生存率为57.8%,5年生存率为46.6%。T1和T2期的5年生存率明显优于T3和T4期(66.7%对27.1%,p < 0.05)。短期客观缓解率(完全缓解和部分缓解)为78.1%。ECT适用于因年老而不宜手术以及放疗或化疗的患者,以及患有全身虚弱或重要器官功能不全的患者。

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Advances in the treatment of malignant tumours by electrochemical therapy (ECT).电化学疗法(ECT)治疗恶性肿瘤的进展
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